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H. Lundbeck A (HLUN-A.CO)
Health Care · Danish CNS/neuroscience pharma · LTM Q1 2026 · Manual deep-dive (Bexicaserin rNPV)
Analysis date: 2026-06-15
Price at analysis: DKK 36.80
Method: mttssn_manual_v1
Conviction: MEDIUM
BUY
Conviction: MEDIUM
A neuroscience pharma in a credible growth transition — Vyepti +54%, Rexulti +19%, record FY25, Q1'26 margin 30% and raised guidance — priced for decline. The manual deep-dive shows the 14.2% headline ROIC is depressed by the zero-earning Bexicaserin right; ex-Bexicaserin adjusted ROIC is 26.9%. At DKK 37 the market prices a near-total Bexicaserin write-off, so the upside is asymmetric. BUY, medium conviction; probability-weighted ~DKK 58 (+57%).
Adj. ROIC
14.2%
WACC 8% → spread +6.2pp
Economic Profit
+DKK 2,197M
+DKK 2.2bn; ex-Bexicaserin ROIC 26.9%
FCF Yield
13.2%
13.2% FCF yield; deleveraging fast
Price / Target
DKK 37 → DKK 60
+63% base; BUY
Revenue (LTM)
DKK 25.5B
LTM; FY25 +13% CER, Q1'26 +21% CER
EBIT Margin
22.6%
Q1'26 EBIT margin 30.2%; FY rising
EV / IC
1.30×
Enterprise value / invested capital
Net Debt
n/a
Net debt DKK 9.1–10.4bn; ND/EBITDA 1.2x
Thesis

Lundbeck is shifting from a legacy-antidepressant base (Brintellix, Cipralex — eroding to generics) to a growth profile led by Vyepti (anti-CGRP migraine, +54% FY25, ~10yr runway) and Rexulti. FY2025 was a record (revenue +13% CER, EBIT +61%) and Q1'26 accelerated (+21% CER, 30.2% EBIT margin, guidance raised), with net-debt/EBITDA down to 1.2x. The manual deep-dive shows the franchise quality the headline hides: strip the zero-earning Bexicaserin right from IC and adjusted ROIC is 26.9%, not 14.2%.

The binary is Bexicaserin (DKK 16,584 carrying, ~47% of intangibles). Its carrying value (MEEM, 9.9% discount rate) implies peak sales ~USD 1.8bn at ~68% probability of success — supportable per IFRS but at the optimistic end; our probability-weighted rNPV is ~DKK 11.7bn (~30% below carrying). Crucially, at DKK 37 the market already prices a near-total write-off: the bear case (Phase III failure → full impairment) values the stub franchise at ~DKK 36 ≈ today's price, so you get the Bexicaserin option and the rest of the pipeline essentially free.

Valuation · reverse-DCF & scenarios

Sum-of-parts: the ex-Bexicaserin franchise (26.9% ROIC) at 9–13x adjusted NOPAT, plus a probability-weighted Bexicaserin rNPV (bear 0 / base ~DKK 13/sh at 60% PoS, USD 1.6bn peak / bull ~DKK 23/sh), less DKK 9.1bn net debt. PEBV 0.68 and EP +DKK 2.2bn corroborate the discount.

Base DKK 60 (+63%), bull DKK 80 (broad Bexicaserin DEE label + amlenetug), bear DKK 36 (Phase III fail, full write-off — roughly today's price) → probability-weighted ~DKK 58 (+57%). A negative first pivotal Bexicaserin readout (~2027) is ~DKK 23/sh below base.

Market-implied growth
-18.5%
NOPAT CAGR over 5y the EV already requires
No-growth value / share
DKK 64
173% of price; rest = priced-in growth
ROIC − WACC
+6.2 pp
ROIC 14.2% vs WACC 8.0% — positive = value creation
CAP (priced-in)
0.0 yrs
years of excess returns the price implies (fades to WACC)

The market pays today’s enterprise value for roughly -18.5% NOPAT growth over 5 years. The business earns 14% on capital against a 8% cost of capital (spread +6.2 pp); the no-growth value is DKK 64/share (173% of price), so the rest is priced-in growth.

Scenario24m targetImpl. gUpsideProb.Driver
BullDKK 80+8%+117%25%Broad Bexicaserin DEE label + amlenetug; pre-commercial assets monetise
BaseDKK 60-2%+63%45%Ex-Bexicaserin franchise (26.9% ROIC) + base Bexicaserin rNPV
BearDKK 36-19%-2%30%Bexicaserin Phase III fail → full write-off (≈ today's price)
Prob-weightedDKK 58+57%100%Scenario-weighted expected value

Sensitivity — fair value / share at WACC × growth

WACC \ g0%3%5%8%10%15%
6.50%9099106117125146
7.25%75828795101117
8.00% (base)646973798495
8.75%556063687180
9.50%495255586167

Green = fair value above the current price of DKK 36.80. The reverse-DCF conclusion is dominated by WACC and growth — see the whole surface, not a single fair value.

Method & data. NOPAT DKK 5,013, invested capital and ROIC 14.2% are observed (adjustments.json); WACC 8.0% and terminal g 2.5% are assumptions. EV→equity uses net debt DKK 9,129. The model holds ROIC constant (no fade) over the explicit horizon; the CAP figure instead fades excess returns to WACC.

⤓ Download the full model (.xlsx) — formula-driven sheets; flex the blue input cells and the model cascades in Excel.

Key drivers

1. Hidden franchise quality

Ex-Bexicaserin adjusted ROIC 26.9% — the 14.2% headline is depressed only by the zero-earning right in IC.

2. Asymmetric Bexicaserin option

Market prices a near-total write-off (bear ~DKK 36 ≈ price); success adds material upside, failure is largely priced in.

3. Vyepti/Rexulti growth

Vyepti +54%, Rexulti +19% FY25 — the growth engines replacing legacy decline.

4. Deleveraging

Net debt DKK 16.2bn→10.4bn, ND/EBITDA 1.2x, EUR 1.5bn undrawn RCF — fast balance-sheet repair.

Key risks
Conclusion

The manual deep-dive resolves the binary: Lundbeck's true franchise quality (ex-Bexicaserin ROIC 26.9%) is masked by an unapproved right that the market already writes off at DKK 37. That makes the risk/reward asymmetric — you own a deleveraging, above-WACC growth pharma with a free shot at Bexicaserin/amlenetug. BUY, medium conviction; base DKK 60, probability-weighted ~DKK 58 (+57%).

The swing factor is the ~2027 Bexicaserin pivotal data; failure costs ~DKK 23/sh from base but is largely priced in. Size for the binary.

Footnote evidence & sources

Every adjustment traces to the cited note/page in the source filing — click to open it there. Annual report / 10-K: 📄 open  ·  Latest interim: 📄 open

Adjustment / figureValueSourceWhy mttssn treats it this way
Goodwill (carrying 31.12.2025)7,008Not 3.1 Intangible assets 📄 p.147Goodwill carrying 7,008 (cost 7,020 - impairment 12). Down from 7,845 due to FX (-825). The entire group = one CGU (FVLCD); the 2025 annual impairment test found NO goodwill impairment beyond 12 MDKK linked to the Italy divestment.
Product rights total (carrying 31.12.2025)28,158Not 3.1 Intangible assets — carrying amount table 📄 p.147Product rights carrying 28,158 (cost 48,267 - accumulated amort/impair 20,109). Not-yet-commercialized product rights = 18,280 (of which Bexicaserin 16,584 + MAGLi/Lu AG12947 1,324 + other). Largest amortizing: Vyepti 8,497, Rexulti 1,381.
Bexicaserin product right (carrying 31.12.2025)16,584Not 3.1 — 'Description of material product rights / Bexicaserin' 📄 p.148THE BINARY. Acquired fair value 18,729 (Dec 2024); carrying 16,584 (2025) / 19,037 (2024); the decline is SOLELY USD/DKK FX. 'Bexicaserin is not yet commercialized; consequently amortization has not commenced.' ~47% of intangible assets in a not-yet-approved right. See the bexicaserin_npv block.
Bexicaserin valuation method (MEEM)NoneNot 5.1 Business combination — valuation method table 📄 p.178'The fair value of the Bexicaserin product right is determined using an income-based multi-period excess earnings method (MEEM) approach, reflecting the total expected revenues from Bexicaserin sales and the product's estimated economic life.' Underpins the carrying-value valuation and my rNPV engine.
Impairment-test discount rate (product rights, pre-tax)0.099Not 3.1 — '2025 testing outcome' 📄 p.150'The impairment tests for product rights are based on a weighted average discount rate, pre-tax, of 9.90% (8.34% in 2024).' The key parameter for carrying-value supportability; used in bexicaserin_npv. Key params explicitly include 'probability of success' (p.149). FVLCD, Level 3. Sensitivity: no reasonable change makes carrying > recoverable amount.
PPA — intangible assets (final fair value)19,255Not 5.1 — final PPA / measurement-period adjustment 📄 p.178Longboard PPA finalized 2025 (IFRS 3): intangibles 19,255 = product rights 18,729 (Bexicaserin) + know-how 526. Provisional 16,453 -> final 19,255 (step-up 2,802). 2024 comparatives restated.
PPA — goodwill (final)1,994Not 5.1 — final PPA table 📄 p.177Goodwill down from provisional 3,949 to final 1,994 — the intangible step-up absorbed goodwill (qualitatively better: the consideration sits in identifiable assets). Net identifiable assets 14,596, total consideration 16,590. DTL final 4,621 (from provisional 3,949). Confirms PPA finalization.
PPA amortization (FY2025, total intangibles)1,483Not 3.1 — amortization line 📄 p.147PPA amortization 1,483 (product rights 1,294 + other intangibles 189). By income-statement line (p.148): COGS 1,323 + S&D 20 + Admin 5 + R&D 135 + Other opex 16 = 1,499 (of which 16 is Italy impairment). mttssn KEEPS this in opex (real cost), add-back REJECTED. Bexicaserin does NOT amortize.
Special items — Adjusted EBITDA reconciliation (FY2025)741Adjusted EBITDA reconciliation (Management Review, not audited) 📄 p.212EBITDA 7,140 -> Adjusted EBITDA 7,881 = +741: Integration -28, Restructuring +406, Impairment +635, Divestment 0, Acquisition 0, Other adjustments -272. Underpins the APM bridge (divergence 4.84%). LTM company special items (EBIT level) = 741 - 29 (Q1'25) + 152 (Q1'26) = 864.
Restructuring cost (FY2025, partnership model)394Not 1.2 — 'Change in the commercial operating model' 📄 p.135DKK 394m severance + direct costs, transition to a partner-led model in 27 markets (announced 9 Sep 2025), in 'Other operating expenses, net'. Normalized out (+ Q1'26 152). Genuine one-off cost.
Italy impairment (FY2025)639Not 1.2 — 'Planned divestment of a non-core production site in Italy' 📄 p.135DKK 639m on the board decision in Dec 2025 to divest a non-core Italian production site. Breakdown: Intangibles 16 + PP&E 430 + Inventories 169 + Other 24. FVLCD Level 2. Normalized (post_tax_addbacks).
Net interest-bearing debt (bank + bond, 31.12.2025)11,185Not 4.4 Bank debt, bond debt, and borrowings 📄 p.166FY2025: EUR bank loan 3,734 (Jun 2027, floating 2.69%) + Eurobond 3,728 (Oct 2027, 0.88%) + Eurobond 3,723 (Jun 2029, 3.38%) = 11,185. Down from 16,174 (acquisition peak) — amortized 8,730 out of cash flow. Q1'26: 10,446 (p.22). Net debt/EBITDA 1.2x.
Tax — effective rate (FY2025)0.289Not 2.3 — 'Explanation of the Group's effective tax rate' 📄 p.142PBT 4,487, tax 1,295 -> 28.9%. Lifted by one-off items: prior-year APA adjustment +4.5pp + valuation allowance (partnership/Italy) +3.4pp. Structural normalized ~21-22%. Pillar II 1 MDKK. Danish joint taxation. LTM effective 27.94% in the build.
Vyepti revenue (FY2025)4,476Not 2.1 Revenue — revenue by product 📄 p.138Vyepti 4,476 (+54% vs 2,909) — US 3,908, Europe 395, Intl 173. Growth driver, anti-CGRP migraine, ~10 years amortization left. Q1'26 +47% CER. Core of the ex-Bexicaserin franchise value.
Rexulti revenue (FY2025)6,205Not 2.1 Revenue — revenue by product 📄 p.138Rexulti 6,205 (+19% vs 5,202) — US 5,745, co-marketing Otsuka, ~4 years amortization left. Largest single product. Q1'26 +22% CER. Second pillar of the in-market franchise. Legacy eroding: Brintellix 4,554 (from 4,847), Cipralex 1,955 (from 2,048).
Analysis history

How the mttssn view has evolved — each prior dated note is preserved.

Quality · Buffett tenets12 / 15
Understandable business
CNS/neuroscience pharma — Vyepti (migraine), Rexulti, Brintellix, plus a deep late-stage pipeline. Legible drug economics, but pipeline/patent dynamics add complexity.
Durable moat
Small/product-specific, not wide: the ex-Bexicaserin franchise earns a strong 26.9% adjusted ROIC, but breadth rests on the pipeline transition while legacy Brintellix/Cipralex erode to generics.
Able & honest management
The Longboard/Bexicaserin deal is strategically focused (neuro-rare build); PPA finalised with goodwill only DKK 2.0bn (the step-up sits in identifiable assets — better quality); net-debt/EBITDA deleveraged 2.3x→1.2x; candid APM.
Financial strength
The 14.2% headline ROIC is depressed purely by the zero-earning Bexicaserin right in IC — ex-Bexicaserin adjusted ROIC is 26.9%. Net debt DKK 16.2bn→10.4bn, EUR 1.5bn undrawn RCF, no near-term refi; EP +DKK 2.2bn.
Margin of safety
Asymmetric: at DKK 37 (9.8x P/E, 13.2% FCF yield) the bear-case ~DKK 36 (full Bexicaserin write-off) ≈ the current price — the market prices a near-total write-off, so the pipeline option (~DKK 16.7/sh book + amlenetug/bocunebart) is essentially free.